Next Gen Sequencing miRNA,PBS,Recombinant Long non-coding RNA CRNDE suppressing cell proliferation

Long non-coding RNA CRNDE suppressing cell proliferation

Prolonged non-coding RNA CRNDE suppressing cell proliferation is regulated by DNA methylation in continuous lymphocytic leukemia

 Prolonged non-coding RNA CRNDE and DNA methylation play a major place inside the prevalence and enchancment of continuous lymphocytic leukemia (CLL). This study tried to analysis the natural place of CRNDE methylation in CLL. The expression and methylation ranges of CRNDE in CLL cell traces (MEC-1 and HG3) sooner than or after methylation inhibitor (5-Aza-2′-deoxycytidine, 5-Aza-CdR) remedy was detected by quantitative real-time PCR or methylation-Explicit PCR.

The connection amongst CRNDE, miR-28 and NDRG2 was verified by luciferase reporter assay. The influence of CRNDE overexpression and 5-Aza-CdR remedy on cell proliferation and apoptosis of MEC-1 and HG3 cells had been assessed by CCK8 and stream cytomery. In distinction with common B lymphocytes, CRNDE was down-regulated and the methylation diploma of CRNDE was elevated in MEC-1 and HG3 cells. Then, 5-Aza-CdR remedy induced an increase of CRNDE expression in MEC-1 and HG3 cells by demethylation.

The overexpression or demethylation of CRNDE inhibited cell proliferation and promoted apoptosis in MEC-1 and HG3 cells by up-regulating CRNDE expression. Moreover, CRNDE functioned as a competing endogenous RNA to repress miR-28, which managed its down-stream purpose NDRG2. CRNDE overexpression inhibited cell proliferation and promoted apoptosis by the use of miR-28/NDRG2 axis in CLL.

In conclusion, our data elaborated that CRNDE expression was regulated by DNA methylation, and the protective influence of CRNDE on CLL was attributed to the inhibition of proliferation in CLL by the use of miR-28/NDRG2 axis. Thus, this work highlights a novel competing endogenous RNA circuitry involving key regulators of CLL.

nexgentek

nexgentek

EUGONIC AGAR

E05-106-2Kg 2 Kg Ask for price

EUGONIC AGAR

E05-106-500g 500 g Ask for price

ENDO AGAR

E05-110-10kg 10 kg
EUR 2381

ENDO AGAR

E05-110-2Kg 2 Kg
EUR 557

ENDO AGAR

E05-110-500g 500 g
EUR 188

APT AGAR

A01-101-10kg 10 kg
EUR 1173

APT AGAR

A01-101-2Kg 2 Kg
EUR 294

APT AGAR

A01-101-500g 500 g
EUR 116

AGAR, BACTERIOLOGICAL

A01-102-10kg 10 kg
EUR 1684

AGAR, BACTERIOLOGICAL

A01-102-2kg 2kg
EUR 405

AGAR, BACTERIOLOGICAL

A01-102-500g 500 g
EUR 146

AGAR, HIGH GEL

A01-102IHG-10kg 10 kg
EUR 2219

AGAR, HIGH GEL

A01-102IHG-2Kg 2 Kg
EUR 521

AGAR, HIGH GEL

A01-102IHG-500g 500 g
EUR 178

AGAR,NOBLE

A01-102N-10kg 10 kg
EUR 3910

AGAR,NOBLE

A01-102N-2kg 2kg
EUR 889

AGAR,NOBLE

A01-102N-500g 500 g
EUR 278

ALT. THIOGLYCOLLATE MED.

A01-103-10kg 10 kg Ask for price

ALT. THIOGLYCOLLATE MED.

A01-103-2Kg 2 Kg Ask for price

ALT. THIOGLYCOLLATE MED.

A01-103-500g 500 g Ask for price

AMIES BROTH WITH CHARCOAL

A01-104-10kg 10 kg Ask for price

AMIES BROTH WITH CHARCOAL

A01-104-2kg 2kg Ask for price

AMIES BROTH WITH CHARCOAL

A01-104-500g 500 g Ask for price

AMIES BROTH W/O CHARCOAL

A01-105-10kg 10 kg Ask for price

AMIES BROTH W/O CHARCOAL

A01-105-2Kg 2 Kg Ask for price

AMIES BROTH W/O CHARCOAL

A01-105-500g 500 g Ask for price

AZIDE BLOOD AGAR BASE

A01-113-10kg 10 kg
EUR 2532

AZIDE BLOOD AGAR BASE

A01-113-2kg 2kg
EUR 589

AZIDE BLOOD AGAR BASE

A01-113-500g 500 g
EUR 197

AZIDE DEXTROSE BROTH

A01-114-10kg 10 kg
EUR 868

AZIDE DEXTROSE BROTH

A01-114-2Kg 2 Kg
EUR 228

AZIDE DEXTROSE BROTH

A01-114-500g 500 g
EUR 98

ANAEROBIC AGAR

A01-115-10kg 10 kg
EUR 2556

ANAEROBIC AGAR

A01-115-2kg 2kg
EUR 595

ANAEROBIC AGAR

A01-115-500g 500 g
EUR 198

A-1 MEDIUM

A01-116-10kg 10 kg
EUR 1034

A-1 MEDIUM

A01-116-2Kg 2 Kg
EUR 264

A-1 MEDIUM

A01-116-500g 500 g
EUR 108

AGAROSE 25G-125G -500G

A01-118-10kg 10 kg Ask for price

AGAROSE 25G-125G -500G

A01-118-2kg 2kg Ask for price

AGAROSE 25G-125G -500G

A01-118-500g 500 g
EUR 494

IL-2 Receptor ?, Human Recombinant

7100-10
EUR 196

IL-2 Receptor ?, Human Recombinant

7100-50
EUR 637

Human CellExp? IL-4 R?, Human Recombinant

7101-10
EUR 229

Human CellExp? IL-4 R?, Human Recombinant

7101-50
EUR 881

Human CellExp? IL-6 R?, Human Recombinant

7102-10
EUR 207

Human CellExp? IL-6 R?, Human Recombinant

7102-50
EUR 800

IL-9, Rat Recombinant

7103-10
EUR 278

IL-9, Rat Recombinant

7103-50
EUR 1132

IL-12p80, Human Recombinant

7104-10
EUR 392

IL-12p80, Human Recombinant

7104-50
EUR 1675

IL-17A, Mouse Recombinant

7105-10
EUR 196

IL-17A, Mouse Recombinant

7105-50
EUR 675

IL-17B, Human Recombinant

7106-10
EUR 196

IL-17B, Human Recombinant

7106-50
EUR 675

IL-17D, Human Recombinant

7107-10
EUR 196

IL-17D, Human Recombinant

7107-50
EUR 675

Human CellExp? IL-34, Human Recombinant

7108-10
EUR 278

Human CellExp? IL-34, Human Recombinant

7108-50
EUR 1132

IL-36RA, Human Recombinant

7109-10
EUR 196

IL-36RA, Human Recombinant

7109-50
EUR 675

IL-36?, Human Recombinant

7110-10
EUR 278

IL-36?, Human Recombinant

7110-50
EUR 1132

IL-36?, Human Recombinant

7111-10
EUR 278

IL-36?, Human Recombinant

7111-50
EUR 1132

Activin B, Human Recombinant

7112-10
EUR 479

Activin B, Human Recombinant

7112-50
EUR 2094

AITRL, Human Recombinant

7113-10
EUR 251

AITRL, Human Recombinant

7113-50
EUR 936

Amphiregulin, Human Recombinant

7114-10
EUR 147

Amphiregulin, Human Recombinant

7114-50
EUR 376

ANG-1, Human Recombinant

7115-10
EUR 251

ANG-1, Human Recombinant

7115-50
EUR 936

ANG-2, Human Recombinant

7116-10
EUR 251

ANG-2, Human Recombinant

7116-50
EUR 936

APRIL, Human Recombinant

7117-10
EUR 311

APRIL, Human Recombinant

7117-50
EUR 1300

APRIL, Mouse Recombinant

7118-10
EUR 196

APRIL, Mouse Recombinant

7118-50
EUR 675

Betacellulin, Murine Recombinant

7119-10
EUR 196

Betacellulin, Murine Recombinant

7119-50
EUR 675

Cardiotrophin-1, Murine Recombinant

7121-10
EUR 278

Cardiotrophin-1, Murine Recombinant

7121-50
EUR 1132

sCD100/Semaphorin-4D, Human Recombinant

7126-10
EUR 251

sCD100/Semaphorin-4D, Human Recombinant

7126-50
EUR 936

CTGFL/WISP-2, Human Recombinant

7129-10
EUR 234

CTGFL/WISP-2, Human Recombinant

7129-50
EUR 860

Human CellExp? DKK-1, Human Recombinant

7132-10
EUR 278

Human CellExp? DKK-1, Human Recombinant

7132-50
EUR 1132

Human CellExp? sDLL-1, Human Recombinant

7133-10
EUR 207

Human CellExp? sDLL-1, Human Recombinant

7133-50
EUR 675

Human CellExp? sDLL-4, Human Recombinant

7134-10
EUR 207

Human CellExp? sDLL-4, Human Recombinant

7134-50
EUR 675

Eotaxin-2/CCL24, murine recombinant

7137-10
EUR 207

Eotaxin-2/CCL24, murine recombinant

7137-50
EUR 675

Eotaxin-3/CCL26, human recombinant

7138-10
EUR 207

Eotaxin-3/CCL26, human recombinant

7138-50
EUR 675

Human CellExp? Fetuin A/ASHG, Human Recombinant

7142-10
EUR 153

Human CellExp? Fetuin A/ASHG, Human Recombinant

7142-50
EUR 381

Histone H3 Peptide, biotin conjugate

7143-01
EUR 240

Histone H3 Peptide, biotin conjugate

7143-1
EUR 1132

Histone H4 Peptide, tetra-acetylated, biotin conjugate

7144-01
EUR 240

Histone H4 Peptide, tetra-acetylated, biotin conjugate

7144-1
EUR 1132

FGF-5, human recombinant

7147-10
EUR 142

FGF-5, human recombinant

7147-50
EUR 359

FGF-6, human recombinant

7148-10
EUR 207

FGF-6, human recombinant

7148-50
EUR 675

FGF-16, human recombinant

7149-10
EUR 207

FGF-16, human recombinant

7149-50
EUR 675

FGF-17, human recombinant

7150-10
EUR 207

Secondary structural various of DNA and RNA associated to CGG/CCG trinucleotide repeat enlargement rationalizes the RNA misprocessing in FXTAS

 CGG tandem repeat enlargement inside the 5′-untranslated space of the fragile X psychological retardation-1 (FMR1) gene ends in unusual nucleic acid conformations, due to this fact inflicting genetic instabilities. We current that the number of G…G (in CGG repeat) or C…C (in CCG repeat) mismatches (apart from A…T, T…A, C…G and G…C canonical base pairs) dictates the secondary structural various of the sense and antisense strands of the FMR1 gene and their corresponding transcripts in fragile X-associated tremor/ataxia syndrome (FXTAS).

The spherical dichroism (CD) spectra and electrophoretic mobility shift assay (EMSA) reveal that CGG DNA (sense strand of the FMR1 gene) and its transcript favor a quadruplex development. CD, EMSA and molecular dynamics (MD) simulations moreover current that further than four C…C mismatches cannot be accommodated inside the RNA duplex consisting of the CCG repeat (antisense transcript); as an alternative, it favors an i-motif conformational intermediate.

Such a alternative for unusual secondary constructions provides a convincing justification for the RNA foci formation due to the sequestration of RNA-binding proteins to the bidirectional transcripts and the repeat-associated non-AUG translation that are seen in FXTAS. The outcomes launched proper right here moreover advocate that small molecule modulators which will destabilize FMR1 CGG DNA and RNA quadruplex constructions might probably be promising candidates for treating FXTAS.

A protracted intergenic non-coding RNA regulates nuclear localization of DNA methyl transferase-1

 DNA methyl transferase-1 or DNMT1 maintains DNA methylation inside the genome and is important for regulating gene expression in cells. Aberrant changes in DNMT1 train and DNA methylation are typically seen in cancers and loads of completely different illnesses. Simply currently, a variety of prolonged intergenic non-protein-coding RNAs or lincRNAs have been confirmed to play a job in regulating DNMT1 train. CCDC26 is a nuclear lincRNA that is steadily mutated in cancers and is a hotbed for disease-associated single nucleotide changes.

Nonetheless, the sensible mechanism of CCDC26 is simply not understood. Proper right here, we current that this lincRNA is focusing on the nuclear periphery. Strikingly, inside the absence of CCDC26 lincRNA, DNMT1 is mis-located inside the cytoplasm, and the genomic DNA is significantly hypomethylated. That’s accompanied by double-stranded DNA breaks and elevated cell dying. These outcomes stage to a beforehand unrecognized mechanism of lincRNA-mediated subcellular localization of DNMT1 and regulation of DNA methylation.

 

Environmental DNA and environmental RNA: Current and potential functions for natural monitoring

 

Standard environmental biomonitoring approaches have limitations in relation to species detectability and their functionality to account for spatial and temporal variation. Furthermore, as invasive strategies they’re typically harmful to explicit particular person organisms, populations and habitats. The equipment of non-invasive sampling methods that extract, isolate and set up nucleic acid sequences (i.e. DNA, RNA) from environmental matrices have very important potential for complementing, and even ultimately altering, current methods of natural environmental analysis.

These environmental DNA (eDNA) and environmental RNA (eRNA) strategies improve spatial and temporal acuity of monitoring, and inside the case of the latter, might current sensible knowledge regarding the nicely being of individuals, and thus ecosystems. Nonetheless, these assessments require robust analysis of issues such as a result of the detectability and specificity of the developed assays.

The launched work highlights the current and future makes use of of nucleic acid-based biomonitoring regimes, with a take care of fish and aquatic invertebrates and their utility for water prime quality, biodiversity and species-specific monitoring. These strategies are compared with typical approaches, with a selected emphasis on the potential insights that might probably be equipped by eRNA analysis, along with some great benefits of microRNAs as assay targets.

 

Extreme-throughput label-free detection of DNA-to-RNA transcription inhibition using brightfield microscopy and deep neural networks

 

Drug discovery is in mounted evolution and foremost advances have led to the occasion of in vitro high-throughput utilized sciences, facilitating the quick analysis of cell phenotypes. One such phenotype is immunogenic cell dying, which occurs partly as a consequence of inhibited RNA synthesis. Automated cell-imaging supplies the potential for combining high-throughput with high-content data acquisition by the simultaneous computation of numerous cell choices. Usually, such choices are extracted from fluorescence pictures, due to this fact requiring labeling of the cells using dyes with attainable cytotoxic and phototoxic destructive results.

Simply currently, deep learning approaches have allowed the analysis of pictures obtained by brightfield microscopy, a manner that was for prolonged underexploited, with the great good thing about avoiding any foremost interference with cell physiology or stimulatory compounds. Proper right here, we describe a label-free image-based high-throughput workflow that exactly detects the inhibition of DNA-to-RNA transcription.

That’s achieved by combining two successive deep convolutional neural networks, allowing (1) to robotically detect cell nuclei (thus enabling monitoring of cell dying) and (2) to classify the extracted nuclear pictures in a binary vogue. This analytical pipeline is R-based and is likely to be merely utilized to any microscopic platform.

 

DNA / RNA Damage Antibody

abx442850-100ug 100 ug
EUR 551

DNA / RNA Damage Antibody

abx443130-100ug 100 ug
EUR 551

DNA / RNA Damage Antibody

abx443410-100ug 100 ug
EUR 537

DNA / RNA Damage Antibody

abx443691-100ug 100 ug
EUR 565

DNA / RNA Damage Antibody

abx443972-100ug 100 ug
EUR 551

DNA / RNA Damage Antibody

abx444253-100ug 100 ug
EUR 551

DNA / RNA Damage Antibody

abx444534-100ug 100 ug
EUR 551

DNA / RNA Damage Antibody

20-abx444884
  • EUR 495.00
  • EUR 328.00
  • 100 ug
  • 25 ug

Mediator Of DNA Damage Checkpoint 1 (MDC1) Antibody (ATTO 565)

abx440635-100ug 100 ug
EUR 551

WSE-6301 Luminograph III Basic/ PC contorl system

Atto-0001 1unit
EUR 15760
Description: 6.0mega Pi xel Cool ed CCD wi r h F0.8

Monoclonal antibody for DNA/RNA Damage

SMC-155C 0.025mg
EUR 190
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Dog | Rabbit DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is not conjugated.

Monoclonal antibody for DNA/RNA Damage

SMC-155D 0.1mg
EUR 332
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Dog | Rabbit DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is not conjugated.

Monoclonal antibody for DNA/RNA Damage

SMC-155D-A390 0.1mg
EUR 379
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Dog | Rabbit DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 390.

Monoclonal antibody for DNA/RNA Damage

SMC-155D-A488 0.1mg
EUR 378
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 488.

Monoclonal antibody for DNA/RNA Damage

SMC-155D-A565 0.1mg
EUR 378
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 565.

Monoclonal antibody for DNA/RNA Damage

SMC-155D-A594 0.1mg
EUR 378
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 594.

Monoclonal antibody for DNA/RNA Damage

SMC-155D-A633 0.1mg
EUR 378
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 633.

Monoclonal antibody for DNA/RNA Damage

SMC-155D-A655 0.1mg
EUR 378
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 655.

Monoclonal antibody for DNA/RNA Damage

SMC-155D-A680 0.1mg
EUR 378
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 680.

Monoclonal antibody for DNA/RNA Damage

SMC-155D-A700 0.1mg
EUR 378
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with ATTO 700.

Monoclonal antibody for DNA/RNA Damage

SMC-155D-ALP 0.1mg
EUR 372
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Alkaline Phosphatase.

Monoclonal antibody for DNA/RNA Damage

SMC-155D-APC 0.1mg
EUR 377
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with APC.

Monoclonal antibody for DNA/RNA Damage

SMC-155D-APCCY7 0.1mg
EUR 450
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with APC/Cy7.

Monoclonal antibody for DNA/RNA Damage

SMC-155D-BI 0.1mg
EUR 374
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Biotin.

Monoclonal antibody for DNA/RNA Damage

SMC-155D-DY350 0.1mg
EUR 393
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Dylight 350.

Monoclonal antibody for DNA/RNA Damage

SMC-155D-DY405 0.1mg
EUR 381
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Dylight 405.

Monoclonal antibody for DNA/RNA Damage

SMC-155D-DY488 0.1mg
EUR 371
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Dylight 488.

Monoclonal antibody for DNA/RNA Damage

SMC-155D-DY594 0.1mg
EUR 373
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Dylight 594.

Monoclonal antibody for DNA/RNA Damage

SMC-155D-DY633 0.1mg
EUR 368
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Dylight 633.

Monoclonal antibody for DNA/RNA Damage

SMC-155D-FITC 0.1mg
EUR 370
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with FITC.

Monoclonal antibody for DNA/RNA Damage

SMC-155D-HRP 0.1mg
EUR 366
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with HRP.

Monoclonal antibody for DNA/RNA Damage

SMC-155D-P594 0.1mg
EUR 385
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with PE/ATTO 594.

Monoclonal antibody for DNA/RNA Damage

SMC-155D-PCP 0.1mg
EUR 377
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with PerCP.

Monoclonal antibody for DNA/RNA Damage

SMC-155D-RPE 0.1mg
EUR 375
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with RPE.

Monoclonal antibody for DNA/RNA Damage

SMC-155D-STR 0.1mg
EUR 376
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is conjugated with Streptavidin.

Monoclonal antibody for DNA/RNA Damage

SMC-155S 0.012mg
EUR 65
Description: A monoclonal antibody from clone 15A3 against Human | Mouse | Rat | Bovine | Monkey | Rabbit | Pig | Dog | Hamster | Chicken | Sheep | Guinea Pig (Cavia porcellus) DNA/RNA Damage. The host species for the production of this antibody is Mouse. The antigen used for immunization is 8-hydroxy-guanosine-BSA and ?casein conjugates. The antibody is tested and validated for IHC, ICC/IF, ELISA, DB, IP, FCM, FA assays with the following recommended dilutions: IHC (1:1000). This MAb for DNA/RNA Damage is not conjugated.

DNA Methyltransferase 1 (DNMT1) Antibody (ATTO 565)

abx440637-100ug 100 ug
EUR 578

DNA Methyltransferase 1 (DNMT1) Antibody (ATTO 565)

abx440647-100ug 100 ug
EUR 565

DNA Methyltransferase 1 (DNMT1) Antibody (ATTO 565)

abx444785-100ug 100 ug
EUR 578

DNA Methyltransferase 3 Like (Dnmt3L) Antibody (ATTO 565)

abx440705-100ug 100 ug
EUR 578

Phosphoserine Antibody (ATTO 565)

abx448303-400ul 400 ul
EUR 592

Phosphothreonine Antibody (ATTO 565)

abx448304-400ul 400 ul
EUR 592

Phosphotyrosine Antibody (ATTO 565)

abx448418-400ul 400 ul
EUR 592

Crotonaldehyde Antibody (ATTO 565)

abx448591-100ug 100 ug
EUR 704

Crotonaldehyde Antibody (ATTO 565)

abx448609-100ug 100 ug
EUR 704

KDEL Antibody (ATTO 565)

abx448663-100ug 100 ug
EUR 606

KDEL Antibody (ATTO 565)

abx448681-100ug 100 ug
EUR 606

KDEL Antibody (ATTO 565)

abx448699-100ug 100 ug
EUR 606

GRP94 Antibody (ATTO 565)

abx448717-100ug 100 ug
EUR 606

Ubiquitin Antibody (ATTO 565)

abx448825-100ug 100 ug
EUR 662

Ubiquitin Antibody (ATTO 565)

abx448843-100ug 100 ug
EUR 662

GST Antibody (ATTO 565)

abx448861-100ug 100 ug
EUR 606

Ubiquitin Antibody (ATTO 565)

abx448879-100ug 100 ug
EUR 662

Metallothionein Antibody (ATTO 565)

abx448897-100ug 100 ug
EUR 606

Metallothionein Antibody (ATTO 565)

abx448915-100ug 100 ug
EUR 606

Metallothionein Antibody (ATTO 565)

abx448933-100ug 100 ug
EUR 606

Tbj51 Antibody (ATTO 565)

abx448969-100ug 100 ug
EUR 606

TbHsp70 Antibody (ATTO 565)

abx448987-100ug 100 ug
EUR 606

CBP Antibody (ATTO 565)

abx449059-100ug 100 ug
EUR 606

CBP Antibody (ATTO 565)

abx449077-100ug 100 ug
EUR 606

SMAD3 Antibody (ATTO 565)

abx449113-100ug 100 ug
EUR 606

SFRP1 Antibody (ATTO 565)

abx449311-100ug 100 ug
EUR 606

PDGFB Antibody (ATTO 565)

abx449401-100ug 100 ug
EUR 606

BAD Antibody (ATTO 565)

abx449455-100ug 100 ug
EUR 606

BAD Antibody (ATTO 565)

abx449473-100ug 100 ug
EUR 606

CDKN2A Antibody (ATTO 565)

abx449491-100ug 100 ug
EUR 606

MEK1 Antibody (ATTO 565)

abx449563-100ug 100 ug
EUR 606

4EBP1 Antibody (ATTO 565)

abx449599-100ug 100 ug
EUR 606

LRP1 Antibody (ATTO 565)

abx449653-100ug 100 ug
EUR 606

LRP1 Antibody (ATTO 565)

abx449671-100ug 100 ug
EUR 606

SFRP2 Antibody (ATTO 565)

abx449689-100ug 100 ug
EUR 606

DKK1 Antibody (ATTO 565)

abx449707-100ug 100 ug
EUR 606

FOXO1 Antibody (ATTO 565)

abx449761-100ug 100 ug
EUR 606

PDGFB Antibody (ATTO 565)

abx449797-100ug 100 ug
EUR 606

Palladin Antibody (ATTO 565)

abx449851-100ug 100 ug
EUR 606

RICTOR Antibody (ATTO 565)

abx449887-100ug 100 ug
EUR 606

Kir4.1 Antibody (ATTO 565)

abx445823-100ug 100 ug
EUR 578

QKI, KH Domain Containing RNA Binding (QKI) Antibody (ATTO 565)

abx440787-100ug 100 ug
EUR 578

Mediator Of DNA Damage Checkpoint 1 (MDC1) Antibody (ATTO 390)

abx440073-100ug 100 ug
EUR 551

Mediator Of DNA Damage Checkpoint 1 (MDC1) Antibody (ATTO 488)

abx440354-100ug 100 ug
EUR 551

Mediator Of DNA Damage Checkpoint 1 (MDC1) Antibody (ATTO 594)

abx440916-100ug 100 ug
EUR 551

Mediator Of DNA Damage Checkpoint 1 (MDC1) Antibody (ATTO 633)

abx441197-100ug 100 ug
EUR 551

Mediator Of DNA Damage Checkpoint 1 (MDC1) Antibody (ATTO 655)

abx441478-100ug 100 ug
EUR 551

Mediator Of DNA Damage Checkpoint 1 (MDC1) Antibody (ATTO 680)

abx441759-100ug 100 ug
EUR 551

Mediator Of DNA Damage Checkpoint 1 (MDC1) Antibody (ATTO 700)

abx442040-100ug 100 ug
EUR 551

WSC-2400 SeesawShaker atto

2312200 1unit
EUR 995

Endoplasmin (GRP94) Antibody (ATTO 565)

abx440564-200ug 200 ug
EUR 592

GRP75 (Grp75) Antibody (ATTO 565)

abx440584-100ug 100 ug
EUR 578

ubiquitin (Ubiquitin) Antibody (ATTO 565)

abx440605-200ug 200 ug
EUR 634

ubiquitin (Ubiquitin) Antibody (ATTO 565)

abx440614-200ug 200 ug
EUR 634

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